20977508
not annotated - annotated - LINNAEUS only
DNA modifications and genome rearrangements during the development and sex differentiation of the bumble bee Bombus terrestris.
Bombus terrestris is a bumble bee that, like most hymenopteran species, exhibits ploidy-specific sex determination controlled by a single sex gene. Depending on their ploidy and the queen pheromone repression, the imagoes differentiate into three castes: males, workers and queens. Here, we focus on the differences of genome organization that occur during development and sex differentiation. We found that cytosine methylation is a significant epigenetic factor with profiles that can be correlated with both processes. We also showed that two kinds of genomic rearrangement occur. The first consists of important DNA amplifications that have sequence profiles that differ in the different developmental instars and sexes. In the second kind, DNA losses also occur, at least involving the mosaic transposable element B. terrestris mosaic repeat 1 (BTMR1).
Ann file
T1 Species 109 126 Bombus terrestris
N1 Reference T1 Taxonomy:30195
T2 Species 130 147 Bombus terrestris
N2 Reference T2 Taxonomy:30195
T3 Species 949 962 B. terrestris
N3 Reference T3 Taxonomy:30195
T4 Out-of-scope 98 108 bumble bee
N4 Reference T4 Taxonomy:28641 Bombus
T5 Out-of-scope 153 163 bumble bee
N5 Reference T5 Taxonomy:28641 Bombus