21091811
not annotated - annotated - LINNAEUS only
Candidate chemosensory ionotropic receptors in a Lepidoptera.
A new family of candidate chemosensory ionotropic receptors (IRs) related to ionotropic glutamate receptors (iGluRs) was recently discovered in Drosophila melanogaster. Through Blast analyses of an expressed sequenced tag library prepared from male antennae of the noctuid moth Spodoptera littoralis, we identified 12 unigenes encoding proteins related to D. melanogaster and Bombyx mori IRs. Their full length sequences were obtained and the analyses of their expression patterns suggest that they were exclusively expressed or clearly enriched in chemosensory organs. The deduced protein sequences were more similar to B. mori and D. melanogaster IRs than to iGluRs and showed considerable variations in the predicted ligand-binding domains; none have the three glutamate-interacting residues found in iGluRs, suggesting different binding specificities. Our data suggest that we identified members of the insect IR chemosensory receptor family in S. littoralis and we report here the first demonstration of IR expression in Lepidoptera.
Ann file
T1 Species 207 230 Drosophila melanogaster
N1 Reference T1 Taxonomy:7227
T2 Species 341 362 Spodoptera littoralis
N2 Reference T2 Taxonomy:7109
T3 Species 419 434 D. melanogaster
N3 Reference T3 Taxonomy:7227
T4 Species 439 450 Bombyx mori
N4 Reference T4 Taxonomy:7091
T5 Species 684 691 B. mori
N5 Reference T5 Taxonomy:7091
T6 Species 696 711 D. melanogaster
N6 Reference T6 Taxonomy:7227
T7 Species 1012 1025 S. littoralis
N7 Reference T7 Taxonomy:7109