21419234
not annotated - annotated - LINNAEUS only
Completing the purine utilisation pathway of Aspergillus nidulans.
We have previously identified by classical genetics and biochemistry, all the genes of Aspergillus nidulans predicted to be involved in purine utilisation, together with cognate regulatory genes and one gene encoding a novel xanthine hydroxylation activity. In this article we complete the description of the purine utilisation pathway with the identification of the two genes (uaX and uaW) encoding the enzymes catalysing the conversion of the product of urate oxidation by urate oxidase, 5-hydroxyisourate, to optically active allantoin. The identification of these additional genes confirms the complete absence of clustering of the genes involved in purine utilisation in A. nidulans.
Ann file
T1 Species 45 65 Aspergillus nidulans
N1 Reference T1 Taxonomy:162425
T2 Species 155 175 Aspergillus nidulans
N2 Reference T2 Taxonomy:162425
T3 Species 744 755 A. nidulans
N3 Reference T3 Taxonomy:162425